ESX1 rabbit pAb
ENT-A13504
Description
| REF | ENT-A13504 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ESX1 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human ESX1 AA range: 327-377 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 80712 |
| Human Swiss Prot Nº | Q8N693 |
| Subcellular Location | Cytoplasm . Nucleus . ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm. |
Other Name:
Background: This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010],