ERK1/2 (1H4) Mouse mAb
ENT-A1603
Description
| Ref | ENT-A1603 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | MAPK, Mitogen-activated protein Kinase, PRKM2,MK01 |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 44,42kDa |
| Human Gene ID | 5594/5595 |
| Human Swiss Prot No | P27361/P28482 |
| Subcellular Location | Nucleus |
Background: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.