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EOMES rabbit pAb

EOMES rabbit pAb

ENT-A2679

Description

 

 

 

REF ENT-A2679
Category Antibody Polyclonal
Description EOMES rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 73kD
Human Gene ID 8320
Human Swiss Prot Nº O95936
Subcellular Location Nucleus .

Other Name: EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2

Background: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],