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EMR4 rabbit pAb

EMR4 rabbit pAb

ENT-A2672

Description

 

 

 

REF ENT-A2672
Category Antibody Polyclonal
Description EMR4 rabbit pAb
Source Rabbit
Applications WB;IF;ELISA
Reactivity Human;Monkey
Reactivity Human;Monkey
Dilution Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human EMR4P. AA range:101-150
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 55kD
Human Gene ID 326342
Human Swiss Prot Nº Q86SQ3
Subcellular Location [Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Secreted .

Other Name: EMR4P; EMR4; GPR127; PGR16; Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16

Background: This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008],