Eme1 rabbit pAb
ENT-A4942
Description
| REF | ENT-A4942 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Eme1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from Eme1 . at AA range: 250-330 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 65kD |
| Human Gene ID | 146956 |
| Human Swiss Prot Nº | Q96AY2 |
| Subcellular Location | Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells. |
Other Name: EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4
Background: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3′-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],