Elk-1 (phospho Ser389) rabbit pAb
ENT-A5138
Description
| REF | ENT-A5138 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Elk-1 (phospho Ser389) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;IP;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Elk1 around the phosphorylation site of Ser389. AA range:356-405 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 48kD |
| Human Gene ID | 2002 |
| Human Swiss Prot Nº | P19419 |
| Subcellular Location | Nucleus. |
Other Name: ELK1; ETS domain-containing protein Elk-1
Background: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012],