EDA rabbit pAb
ENT-A7839
Description
| REF | ENT-A7839 |
|---|---|
| Category | Antibody Polyclonal |
| Description | EDA rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human EDA. AA range:120-170 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 42kD |
| Human Gene ID | 1896 |
| Human Swiss Prot Nº | Q92838 |
| Subcellular Location | Cell membrane ; Single-pass type II membrane protein .; [Ectodysplasin-A, secreted form]: Secreted . |
Other Name: EDA; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein
Background: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],