E2F-3 (Acetyl Lys168) rabbit pAb
ENT-A7896
Description
| REF | ENT-A7896 |
|---|---|
| Category | Antibody Polyclonal |
| Description | E2F-3 (Acetyl Lys168) rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB: 1:500-10000 ELISA: 1:10000 |
| Immunogen | Synthesized acetyl-peptide from human protein at AA range: 130-200 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 50kD |
| Human Gene ID | 1871 |
| Human Swiss Prot Nº | O00716 |
| Subcellular Location | Nucleus. |
Other Name: E2F3 KIAA0075
Background: This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013],