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E-Ras rabbit pAb

E-Ras rabbit pAb

ENT-A5732

Description

 

 

 

REF ENT-A5732
Category Antibody Polyclonal
Description E-Ras rabbit pAb
Source Rabbit
Applications WB;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human ERAS. AA range:184-233
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 25kD
Human Gene ID 3266
Human Swiss Prot Nº Q7Z444
Subcellular Location Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Other Name: ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras

Background: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012],