DTNA rabbit pAb
ENT-A13594
Description
| REF | ENT-A13594 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DTNA rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human DTNA AA range: 131-181 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 1837 |
| Human Swiss Prot Nº | Q9Y4J8 |
| Subcellular Location | Cytoplasm. Cell junction, synapse. Cell membrane . In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane. . |
Other Name:
Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],