Dok-2 (phospho Tyr299) rabbit pAb
ENT-A1807
Description
| REF | ENT-A1807 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Dok-2 (phospho Tyr299) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IF;ELISA |
| Reactivity | Human;Mouse;Monkey |
| Reactivity | Human;Mouse;Monkey |
| Dilution | Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 48kD |
| Human Gene ID | 9046 |
| Human Swiss Prot Nº | O60496 |
| Subcellular Location | cytosol, |
Other Name: DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2)
Background: docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],