DOCK4 rabbit pAb
ENT-A13620
Description
| REF | ENT-A13620 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DOCK4 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human DOCK4 AA range: 533-583 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 9732 |
| Human Swiss Prot Nº | Q8N1I0 |
| Subcellular Location | Cell membrane . Cell projection . Cytoplasm, cytosol . Colocalizes with EPHA2, RHOG and CTTN/cortactin at the tip of protrusions in migrating cells. . |
Other Name:
Background: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008],