Dkk-1 rabbit pAb
ENT-A4412
Description
| REF | ENT-A4412 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Dkk-1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 29kD |
| Human Gene ID | 22943 |
| Human Swiss Prot Nº | O94907 |
| Subcellular Location | Secreted. |
Other Name: DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK
Background: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],