DAPK1 (Phospho-Ser308) rabbit pAb
ENT-A13705
Description
| REF | ENT-A13705 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DAPK1 (Phospho-Ser308) rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | IHC-p 1:50-200, WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human DAPK1 (Phospho-Ser308) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 160kD |
| Human Gene ID | 1612 |
| Human Swiss Prot Nº | P53355 |
| Subcellular Location | [Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton. |
Other Name: Death-associated protein kinase 1 (DAP kinase 1;EC 2.7.11.1)
Background: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],