CXCL2 rabbit pAb
ENT-A15798
Description
| REF | ENT-A15798 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CXCL2 rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human GROβ AA range: 58-107 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 2920 |
| Human Swiss Prot Nº | P19875 |
| Subcellular Location | Secreted. |
Other Name: C-X-C motif chemokine 2 (Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha) [Cleaved into: GRO-beta(5-73;GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353)]
Background: function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,