CSH1 rabbit pAb
ENT-A7955
Description
| REF | ENT-A7955 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CSH1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 161-210 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 25kD |
| Human Gene ID | 1442 |
| Human Swiss Prot Nº | P01243 |
| Subcellular Location | extracellular region,endoplasmic reticulum,vesicle,membrane-bounded vesicle, |
Other Name: CSH1; CSH2
Background: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, al