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CRM1 rabbit pAb

CRM1 rabbit pAb

ENT-A15784

Description

 

 

 

REF ENT-A15784
Category Antibody Polyclonal
Description CRM1 rabbit pAb
Source Rabbit
Applications WB; ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution WB 1:1000-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human CRM1
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 7514
Human Swiss Prot Nº O14980
Subcellular Location Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.

Other Name: Exportin-1 (Exp1;Chromosome region maintenance 1 protein homolog)

Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],