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CREB Mouse mAb

CREB Mouse mAb

ENT-A1535

Description

Ref ENT-A1535
Category Antibody Monoclonal
Alternative Name Cyclic AMP-responsive element binding protein 1 antibody, MGC9284 antibody, CREB1 antibody
Application WB, IHC
Source Mouse
Reactivity Human, Mouse
Dilution WB 1:500-1,000    IHC 1:100-200
Immunogen Recombinant Protein
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 43kDa
Human Gene ID 1385
Human Swiss Prot No P16220
Subcellular Location Nucleus

Background: CREB (cAMP response element-binding protein) is a cellular transcription factor. This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB is closely related in structure and function to CREM (cAMP response element modulator) and ATF-1 (activating transcription factor-1) proteins. CREB proteins are expressed in many animals.