CR3L3 rabbit pAb
ENT-A10040
Description
| REF | ENT-A10040 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CR3L3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 1-100 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 50kD |
| Human Gene ID | 84699 |
| Human Swiss Prot Nº | Q68CJ9 |
| Subcellular Location | Endoplasmic reticulum membrane ; Single-pass type II membrane protein .; [Processed cyclic AMP-responsive element-binding protein 3-like protein 3]: Nucleus . Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. |
Other Name:
Background: This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],