Corticotropin-releasing factor receptor 2 rabbit pAb
ENT-A7986
Description
| REF | ENT-A7986 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Corticotropin-releasing factor receptor 2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat |
| Reactivity | Human;Rat |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 221-295 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 48kD |
| Human Gene ID | 1395 |
| Human Swiss Prot Nº | Q13324 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . |
Other Name: Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2)
Background: The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011],