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Connexin-32 rabbit pAb

Connexin-32 rabbit pAb

ENT-A5525

Description

 

 

 

REF ENT-A5525
Category Antibody Polyclonal
Description Connexin-32 rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human Connexin-32. AA range:66-115
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 32kD
Human Gene ID 2705
Human Swiss Prot Nº P08034
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Other Name: GJB1; CX32; Gap junction beta-1 protein; Connexin-32; Cx32; GAP junction 28 kDa liver protein

Background: This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2008],