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Collagen I (4B5) Mouse mAb

Collagen I (4B5) Mouse mAb

ENT-A1625

Description

Ref ENT-A1625
Category Antibody Monoclonal
Alternative Name Alpha 1 type I collagen, COL1A1, COL1A3
Application IHC
Source Mouse
Reactivity Human, Mouse, Rat
Dilution IHC 1:100-200
Immunogen Synthetic Peptide
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 139kDa
Human Gene ID 1277/1278
Human Swiss Prot No P02452
Subcellular Location Secreted,extracellular space,extracellular matrix

Background: Type 1 collagen is a trimeric complex comprised of two molecules of COL1A1 (alpha-1 type 1 collagen) and one molecule of COL1A2 (alpha-2 type 1 collagen). The expression levels of COL1A1 are regulated by multiple mechanisms, including mRNA stability, translation, and posttranslational modification.