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CLD9 rabbit pAb

CLD9 rabbit pAb

ENT-A8847

Description

 

 

 

REF ENT-A8847
Category Antibody Polyclonal
Description CLD9 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from part region of human protein
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 23kD
Human Gene ID 9080
Human Swiss Prot Nº O95484
Subcellular Location Cell junction, tight junction. Cell membrane ; Multi-pass membrane protein .

Other Name:

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Jun 2010],