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CLC-KA rabbit pAb

CLC-KA rabbit pAb

ENT-A2434

Description

 

 

 

REF ENT-A2434
Category Antibody Polyclonal
Description CLC-KA rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human CLCNKA. AA range:581-630
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 75kD
Human Gene ID 1187
Human Swiss Prot Nº P51800
Subcellular Location Membrane; Multi-pass membrane protein.

Other Name: CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1

Background: This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],