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CK8 Mouse mAb

CK8 Mouse mAb

ENT-A1434

Description

Ref ENT-A1434
Category Antibody Monoclonal
Alternative Name CARD2, CYK8, Cytokeratin 8, K2C8, K8, keratin 8, KO, KRT8, Type II keratin Kb8
Application WB, IHC
Source Mouse
Reactivity Human, Rat, Mouse
Dilution WB 1:2,000-5,000 IHC 1:200
Immunogen Synthetic Peptide
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 54kDa
Human Gene ID 3856
Human Swiss Prot No P05787
Subcellular Location Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.

Background: Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas.