CHOP (2B1) Mouse mAb
ENT-A1598
Description
| Ref | ENT-A1598 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | GADD153, DDIT3,MGC4154 |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 27kDa |
| Human Gene ID | 1649 |
| Human Swiss Prot No | P35638 |
| Subcellular Location | Nucleus |
Background: CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase.