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CEP85 rabbit pAb

CEP85 rabbit pAb

ENT-A13950

Description

 

 

 

REF ENT-A13950
Category Antibody Polyclonal
Description CEP85 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse
Reactivity Human; Mouse
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human CEP85 AA range: 267-317
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 85kD
Human Gene ID 64793
Human Swiss Prot Nº Q6P2H3
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Nucleus, nucleolus . Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856). .

Other Name: Centrosomal protein of 85 kDa (Coiled-coil domain-containing protein 21)

Background: This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],