Cdc42EP4 rabbit pAb
ENT-A5368
Description
| REF | ENT-A5368 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Cdc42EP4 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BORG4. AA range:201-250 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 36kD |
| Human Gene ID | 23580 |
| Human Swiss Prot Nº | Q9H3Q1 |
| Subcellular Location | Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. |
Other Name: CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4
Background: The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008],