CD86 rabbit pAb
ENT-A15782
Description
| REF | ENT-A15782 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CD86 rabbit pAb |
| Source | Rabbit |
| Applications | WB; IF; ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000; IF/ICC 1:100-500; ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human CD86 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 942 |
| Human Swiss Prot Nº | P42081 |
| Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Other Name: T-lymphocyte activation antigen CD86 (Activation B7-2 antigen;B70;BU63;CTLA-4 counter-receptor B7.2;FUN-1;CD antigen CD86)
Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011],