CD41/Integrin α/2b Mouse mAb
ENT-A1474
Description
| Ref | ENT-A1474 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | BDPLT2,CD41 antigen, CD41a, gp2b, ITGA2B, platelet fibrinogen receptor alpha |
| Application | IHC |
| Source | Mouse |
| Reactivity | Human |
| Dilution | IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | |
| Human Gene ID | 3674 |
| Human Swiss Prot No | P08514 |
| Subcellular Location | Membrane |
Background: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation.