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CD294 rabbit pAb

CD294 rabbit pAb

ENT-A4290

Description

 

 

 

REF ENT-A4290
Category Antibody Polyclonal
Description CD294 rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2. AA range:161-210
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 43kD
Human Gene ID 11251
Human Swiss Prot Nº Q9Y5Y4
Subcellular Location Cell membrane ; Multi-pass membrane protein . Internalized receptors colocalized with RAB11A. .

Other Name: PTGDR2; CRTH2; DL1R; GPR44; Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD294

Background: This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3′ UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011],