CD151 rabbit pAb
ENT-A8052
Description
| REF | ENT-A8052 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CD151 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 91-140 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 977 |
| Human Swiss Prot Nº | P48509 |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
Other Name: CD151 antigen (GP27;Membrane glycoprotein SFA-1;Platelet-endothelial tetraspan antigen 3;PETA-3;Tetraspanin-24;Tspan-24;CD antigen CD151)
Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008],