CD141 rabbit pAb
ENT-A7120
Description
| REF | ENT-A7120 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CD141 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | 7056 |
| Human Swiss Prot Nº | P07204 |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
Other Name: THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
Background: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],