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CCNT2 rabbit pAb

CCNT2 rabbit pAb

ENT-A9801

Description

 

 

 

REF ENT-A9801
Category Antibody Polyclonal
Description CCNT2 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human protein . at AA range: 510-590
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 80kD
Human Gene ID 905
Human Swiss Prot Nº O60583
Subcellular Location Cytoplasm, perinuclear region . Nucleus . Nucleus in differentiating cells. .

Other Name:

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],