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Cathepsin H rabbit pAb

Cathepsin H rabbit pAb

ENT-A1654

Description

 

 

 

REF ENT-A1654
Category Antibody Polyclonal
Description Cathepsin H rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen Synthesized peptide derived from Cathepsin H . at AA range: 70-150
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 40kD
Human Gene ID 1512
Human Swiss Prot Nº P09668
Subcellular Location Lysosome.

Other Name: CTSH; CPSB; Pro-cathepsin H

Background: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],