Caspase 9 Mouse mAb
ENT-A1456
Description
| Ref | ENT-A1456 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody |
| Application | WB, IP, IF |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-5,000 IP 1:200 IF 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 47（51）kDa |
| Human Gene ID | 842 |
| Human Swiss Prot No | P55211 |
| Subcellular Location | Cytosol,Mitochondrion,Nucleus |
Background: Caspase-9 is an initiator caspase, encoded by the CASP9 gene.Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).