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Carcinoembryonic Antigen/CEA Mouse mAb

Carcinoembryonic Antigen/CEA Mouse mAb

ENT-A1440

Description

Ref ENT-A1440
Category Antibody Monoclonal
Alternative Name Carcinoembryonic antigen, CD66e, CEACAM5, Meconium antigen 100
Application IHC
Source Mouse
Reactivity Human, Rat, Mouse
Dilution IHC 1:200
Immunogen Synthetic Peptide
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 113kDa
Human Gene ID 1048
Human Swiss Prot No P06731
Subcellular Location

Background: CEA is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).