Calnexin Rabbit pAb
ENT-A1247
Description
| REF | ENT-A1247 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Calnexin Rabbit pAb |
| Source | Rabbit |
| Applications | WB, IHC |
| Reactivity | Human, Rat, Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 75,80,90kDa |
| Human Gene ID | 821 |
| Human Swiss Prot Nº | P27824 |
| Subcellular Location | Endoplasmic reticulum membrane,Melanosome. |
Other Name: CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody
Background: Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.