Cacna2d4 rabbit pAb
ENT-A2294
Description
| REF | ENT-A2294 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Cacna2d4 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CACNA2D4. AA range:548-597 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 130kD |
| Human Gene ID | 93589 |
| Human Swiss Prot Nº | Q7Z3S7 |
| Subcellular Location | Membrane ; Single-pass type I membrane protein . |
Other Name: CACNA2D4; Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-gated calcium channel subunit alpha-2/delta-4
Background: calcium voltage-gated channel auxiliary subunit alpha2delta 4(CACNA2D4) Homo sapiens This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],