c-Myb (Acetyl Lys471) rabbit pAb
ENT-A15643
Description
| REF | ENT-A15643 |
|---|---|
| Category | Antibody Polyclonal |
| Description | c-Myb (Acetyl Lys471) rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human c-Myb (Acetyl Lys471) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 70kD |
| Human Gene ID | 4602 |
| Human Swiss Prot Nº | P10242 |
| Subcellular Location | Nucleus . |
Other Name: Transcriptional activator Myb (Proto-oncogene c-Myb)
Background: domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5′-YAAC[GT]G-3′. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,