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C-Jun (Hydroxylated-p244) rabbit pAb

C-Jun (Hydroxylated-p244) rabbit pAb

ENT-A15860

Description

 

 

 

REF ENT-A15860
Category Antibody Polyclonal
Description C-Jun (Hydroxylated-p244) rabbit pAb
Source Rabbit
Applications WB; ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution WB 1:1000-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human C-Jun (Hydroxylated-p244)
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 39-42kD
Human Gene ID 3725
Human Swiss Prot Nº P05412
Subcellular Location Nucleus.

Other Name: Transcription factor AP-1 (Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39)

Background: function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′.,PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.,