BRSK2 (Phospho Thr260) rabbit pAb
ENT-A15700
Description
| REF | ENT-A15700 |
|---|---|
| Category | Antibody Polyclonal |
| Description | BRSK2 (Phospho Thr260) rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human BRSK2 (Phospho Thr260) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 78kD |
| Human Gene ID | 9024 |
| Human Swiss Prot Nº | Q8IWQ3 |
| Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Endoplasmic reticulum. Detected at centrosomes during mitosis. Localizes to the endoplasmic reticulum in response to stress caused by tunicamycin. |
Other Name: Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1;Brain-selective kinase 2;EC 2.7.11.26;Brain-specific serine/threonine-protein kinase 2;BR serine/threonine-protein kinase 2;Serine/threonine-protein kinase 29;Serine/threonine-protein kinase SAD-A)
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,