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BGH3 rabbit pAb

BGH3 rabbit pAb

ENT-A10434

Description

 

 

 

REF ENT-A10434
Category Antibody Polyclonal
Description BGH3 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human protein . at AA range: 230-310
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 75kD
Human Gene ID 7045
Human Swiss Prot Nº Q15582
Subcellular Location Secreted . Secreted, extracellular space, extracellular matrix . May be associated both with microfibrils and with the cell surface (PubMed:8077289). .

Other Name:

Background: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008],