Beclin-1 (5C2) Mouse mAb
ENT-A1591
Description
| Ref | ENT-A1591 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | ATG6, Bcl-2 interacting protein beclin, BECN1, Coiled coil myosin like BCL2 interacting protein |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 60kDa |
| Human Gene ID | 8678 |
| Human Swiss Prot No | Q14457 |
| Subcellular Location | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Mitochondrion, Nucleus |
Background: Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1.