BD1L1 rabbit pAb
ENT-A9347
Description
| REF | ENT-A9347 |
|---|---|
| Category | Antibody Polyclonal |
| Description | BD1L1 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | IHC-p 1:50-300 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1280-1360 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 335kD |
| Human Gene ID | 259282 |
| Human Swiss Prot Nº | Q8NFC6 |
| Subcellular Location | Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. . |
Other Name:
Background: Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.