BCL3 rabbit pAb
ENT-A8307
Description
| REF | ENT-A8307 |
|---|---|
| Category | Antibody Polyclonal |
| Description | BCL3 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;WB |
| Reactivity | Human;Rat;Mouse;;Goat |
| Reactivity | Human;Rat;Mouse;;Goat |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 340-420 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 49kD |
| Human Gene ID | 602 |
| Human Swiss Prot Nº | P20749 |
| Subcellular Location | Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via ‘Lys-63’-linked ubiquitin chains is required for nuclear accumulation. . |
Other Name:
Background: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008],