Bcl-2 (phospho Ser70) rabbit pAb
ENT-A1781
Description
| REF | ENT-A1781 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Bcl-2 (phospho Ser70) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;IP;ELISA |
| Reactivity | Human;Monkey |
| Reactivity | Human;Monkey |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Ser70. AA range:41-90 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 26kD |
| Human Gene ID | 596 |
| Human Swiss Prot Nº | P10415 |
| Subcellular Location | Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Cytoplasm . |
Other Name: BCL2; Apoptosis regulator Bcl-2
Background: BCL2, apoptosis regulator(BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],