Bax (6F11) Mouse mAb
ENT-A1577
Description
| Ref | ENT-A1577 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | Apoptosis regulator bax, BAXA, BCL2 associated X protein |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 20kDa |
| Human Gene ID | 581 |
| Human Swiss Prot No | Q07812 |
| Subcellular Location | Cytoplasm, Membrane, Mitochondrion |
Background: Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane.