BACE2 rabbit pAb
ENT-A10610
Description
| REF | ENT-A10610 |
|---|---|
| Category | Antibody Polyclonal |
| Description | BACE2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 210-290 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 56kD |
| Human Gene ID | 25825 |
| Human Swiss Prot Nº | Q9Y5Z0 |
| Subcellular Location | Cell membrane ; Single-pass type I membrane protein . Golgi apparatus . Endoplasmic reticulum. Endosome. |
Other Name:
Background: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer’s disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],