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B2MG rabbit pAb

B2MG rabbit pAb

ENT-A10595

Description

 

 

 

REF ENT-A10595
Category Antibody Polyclonal
Description B2MG rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse
Reactivity Human;Rat;Mouse
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human protein . at AA range: 40-120
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 13kD
Human Gene ID 567
Human Swiss Prot Nº P61769
Subcellular Location Secreted . Cell surface . Detected in serum and urine (PubMed:1336137, PubMed:7554280). .; (Microbial infection) In the presence of M.tuberculosis EsxA-EsxB complex decreased amounts of B2M are found on the cell surface (PubMed:25356553). .

Other Name:

Background: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014],